Managing these typically high-value products means addressing the risk of container breakages, and the risk of particle contamination which is an increasing area of concern for regulatory bodies, as highlighted by the introduction of the revised GMP Annex 1 for the manufacture of sterile medicinal products. In the context of these growing pressures, ready-to-use (RTU) containers are experiencing growing demand.
As they are supplied washed, pre-siliconized (if required), and sterilized, these components are ready to be integrated directly into aseptic fill and finish lines, avoiding the need for several preparation procedures to be carried out, including washing, drying, and depyrogenation.
RTU cartridges are used for a broad range of hand-held injection devices such as pens, auto-injectors, and on-body delivery systems, meeting the expectations of increasing numbers of pharma companies that have intensified their focus on drug delivery devices that patients can use in their own homes.
Nexa® EZ-fill® cartridges offer unparalleled quality. Our world-leading process efficiency and operations help reduce the risk of contamination, rejections, complaints and recalls.
Our ready-to-use Nexa® EZ-fill® cartridges are designed for optimizing the fill & finish process and the performance with drug delivery systems offering the following attributes:
Small-volume RTU cartridges are designed to cope with the demands of delivering precise, small amounts of drugs such as GLP-1 for the treatment of diabetes and obesity, insulin, and hormones – with a choice of nest-and-tub and/or nest-and-tray configurations.
Large-volume RTU cartridges are best suited to the delivery of high-value biologics for the treatment of conditions such as cancer and Parkinson’s and autoimmune diseases.
Read more about our EZ-fill® cartridges and discover their compatibility with devices ranging from injection devices to on-body delivery systems.