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Drug Containment Solutions

Advanced Cartridge Systems for Pharmaceutical Applications

With over 75 years of experience in glass production, Stevanato Group is currently the market leader in cartridge systems manufacturing.

Our knowledge in drug containment solutions ensures high quality glass cartridges for parenteral applications, and they are designed for hand-held or wearable injection devices. These devices are frequently employed for biologic medications like insulin, GLP-1, growth, and fertility hormones as well as for immunology, oncology, cardiovascular and metabolic disorders.

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Cartridges for self-administered injectable therapies

Our highly-accurate glass converting process includes:

  • Extended 100% temperature control by pyrometers

  • Monitoring of forming speed (rotation and tool speed)

  • 100% in-line dimensional controls for the most critical/crucial dimensions and statistical in-process controls

  • Optimized tool design and use of new materials for improved handling of the cartridges

  • 100% in-line camera control for cosmetic defects

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With complete control of the forming conditions and through continuous product improvements, we can ensure:

  • Internal shape optimization to maximize dosing accuracy
  • High glass resistance from external forces acting on the primary packaging such as drug delivery systems
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Ready-to-use glass cartridges for parenteral applications

The continued drive to improve efficiency and quality places consequent emphasis on the need to reduce pharmaceutical manufacturing complexity and limit component handling while minimizing resource usage. At the same time, it’s equally important to uphold high-quality standards and increase flexibility.

Our cartridges are available in a ready-to-use (RTU) configuration. They are washed, siliconized, capped (optional) and sterilized, making them suitable for processing on both new and existing fill and finish lines.

Explore the advantages of our EZ-fill® ready-to-use cartridges, crafted to simplify pharmaceutical processes by avoiding several production steps, such as siliconization, crimping and sterilization, and increasing your flexibility in fill and finish process. Learn more about EZ-fill®

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Explore our portfolio of pharmaceutical cartridge solutions

To support your specific formulation and dosage requirements, our portfolio is compatible with the main device platform and includes:

  • Small-volume cartridges (1.5mL to 3mL): highly accurate formats, ideal for standard pen injector cartridges and multi-dose therapies
  • Large-volume cartridges (5mL to 20mL): specifically designed to provide a safe and reliable cartridge for self administration in high-volume or on-body delivery systems

Cartridge systems regulatory compliance

Our cartridges are compliant with PH.Eur., USP and JP for applicable parts; our Regulatory Affairs team can support customer drug applications and provide authorization of DMF submissions to US FDA, Health Canada, as well as for other regional authorities.

Find out our glass cartridges portfolio

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Nexa® Glass Cartridges

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Fina® Glass Cartridges

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Large-Volume Glass Cartridges

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Dual-Chamber Cartridges

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Add-on components for cartridge systems: enhancing containment solutions

Collaborating with the best-in-class components manufacturers, and with an expert team, Stevanato Group can suggest the most adequate cartridge elastomeric components, depending on the final application of the drug.

The cartridge systems comprise a glass barrel, a plunger and a lined cap (aluminum cap + lined rubber) or a vial crimp (aluminum cap + rubber front stopper). Depending on the application and fill and finish process, the cartridges components vary in sizes, formulation, and design.

Add-on components

Caps Lined

Lined caps (for 7.15mm finish)

  • Mono-layer for mono-injections
  • Bi-layer for multiple punctures
  • Different sesigns / suppliers / formulations
  • Serum
  • Coated
  • Alu-cap with or without flip-off
  • Different designs / suppliers / formulations
Caps Alu

Front stoppers and alu-caps (for 13mm finish)

  • Serum
  • Coated
  • Alu-cap with or without flip-off
  • Different designs / suppliers / formulations

Explore cartridge systems media and resources

Download our brochure on EZ-fill® RTU cartridge containers.

Find more on product range and advantages of RTU cartridges
Download now
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Read the white paper about RTU cartridges compatibility for GLP-1-based drugs

Find out how RTU cartridges are a viable solution for GLP-1 applications for both autoinjectors and pen injectors

Analytical services for cartridges

Discover our testing services for cartridge containment selection

With over 10 years of know-how throughout the Technology Excellence Centers, we support you in defining and running the best testing protocol to assess the performance and compatibility between your product, the containment system, and relevant delivery devices such as pen injectors.

Our Technology Excellence Centers can be your strategic partner performing comparison and compatibility testing throughout the product development lifecycle. Early testing minimizes the risk of a future re-formulation or container re-validation while in clinical development, or worse to re-call your product after the launch in the market. 

Learn more
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Interested in Cartridge Systems?

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