EZ-fill® Platform for Ready-to-Use Pharmaceutical Vials, Cartridges, and Syringes Containers

Many Pharmaceutical companies are looking for ways to lower their footprint and reduce total costs by relying on experienced external partners for non-core activities.

Ready-to-use packaging greatly simplifies the overall filling process, largely eliminating the need for the pharmaceutical industry to perform steps such as washing, siliconization* depyrogenation*, closures assembly* and sterilization, which are typical processes involved in the preparation of primary containers prior to filling.

*when applicable

With EZ-fill®, we offer sterilized glass containers for pharmaceutical use, including vials, cartridges, and syringes designed to support efficient aseptic manufacturing.

When it comes to RTU containment solutions for biopharmaceutical products, no solution matches EZ-fill® platform, whose proven advantages have turned its processing technology into an industry standard.

Adopted by the leading glass primary packaging suppliers worldwide, EZ-fill® has become the market’s most established choice for sterilized containers.

This success is also supported by an ecosystem of compatible technologies and qualified partners.

Other players have chosen EZ-fill® technology for their secondary packaging. Our Standard secondary packaging ensures full compatibility with fill and finish technologies.

Our close collaboration with key providers of ready-to-use closures and add-on components allows us to offer not only glass primary packaging, but fully compliant containment systems.

Rubber components

EZ-fill® pharmaceutical solutions can de-risk pharma companies’ operations.

EZ-fill® sterilized containers help pharmaceutical companies simplify aseptic filling while reducing operational complexity and maintaining the highest quality. By removing several preparation steps typically performed before filling, the platform supports more efficient manufacturing, greater flexibility across formats and batch sizes, and a smoother transition from development to commercial production.

Pharma companies can de-risk operations and ease their manufacturing process by reducing human intervention and removing critical operating units affecting the quality of the drug product.

Patient safety is at the heart of container design and engineering. By separating all containers in the secondary packaging, EZ-fill® ensures maximum integrity of the sterilized containers during transportation and in buffering/in-feeding operations, while minimizing glass-to-glass contact.

This allows for an effective mitigation of the risk of breakages, cosmetic issues and particle generation. In turn, it brings significant advantages, both mechanically and in performance, because it reduces production stops and rejects during inspection.

RTU solutions can be a suitable, time-efficient and cost-effective answer to meet GMP Annex 1 regulation requirements.

• Flexibility in packaging: different primary containers can be processed on the same aseptic filling line without changing the infeed module
• Flexibility in F&F process: EZ-fill® packaging (N&T and Tray) is compatible with all fill and finish Technologies. Different requirements in terms of line speed and batch dimension can be met through automation level of infeed and EZ-fill® packaging choice

Reduced total cost of ownership (TCO) mainly driven by improved efficiency of the aseptic filling, reduced waste and investments.

By using EZ-fill® configuration in aseptic filling process guarantees a reduction of costs of upstream operations, reduction of quality issues (hidden costs) associated with non-core activities and improvement of operation efficiency.

No change in primary packaging across development and commercial phases can streamline characterization and validation processes. Also, the flexibility to exploit fill and finish multi-purpose lines for cartridges and syringes reduces the time-to-market.

Explore technical resources dedicated to EZ-fill® ready-to-use pharmaceutical containers, RTU containment solutions, GMP Annex 1 requirements, and the benefits of sterilized vials, cartridges, and syringes for aseptic manufacturing.